SLU-PP-332 Research Compound: Identity, Specifications, COA and Where to Buy in the USA

SLU-PP-332 is a synthetic estrogen-related receptor (ERRα/β/γ) agonist developed at Saint Louis University School of Medicine. Before ordering, match the supplier's listing against these identifiers:

A listing whose formula, CAS number or molecular weight does not match these values is a red flag regardless of price.

SLU-PP-332 is sold by many peptide vendors and is often searched for as "SLU-PP-332 peptide", but it is a small molecule, not a peptide. It has no amino acid residues and no peptide bonds. This matters practically: peptide-specific tests such as amino acid analysis or peptide content do not apply, while identity confirmation relies on the small-molecule methods described below.

A research-grade lot should be supplied with:

• Purity by HPLC: reported as percent area of the main peak, with the chromatogram available.
• Identity by mass spectrometry: the monoisotopic mass of C₁₈H₁₄N₂O₂ is 290.11, so in positive electrospray the protonated ion [M+H]⁺ is expected near m/z 291.1.
• Appearance: the physical form of the solid as observed for the lot.
• Net content per vial, for example 10 mg.
• Lot number printed on the vial and matching the COA.

Some suppliers also provide ¹H NMR data, which is useful for confirming the hydrazone structure and spotting residual solvents.

A COA is only useful if it describes the vial in hand. Check that it includes:

1. The compound name, CAS number and formula, matching the identity table above.
2. A lot or batch number identical to the vial label.
3. The HPLC method summary and the purity result, ideally with the chromatogram.
4. The mass spectrum or observed m/z value.
5. The date of analysis and the laboratory that performed it.

Generic COAs with no lot number, or a single COA reused across many years of product, cannot verify a specific batch. NuRev posts lot-specific documentation on its Certificates of Analysis page.

SLU-PP-332 is supplied as a dry solid. General handling practice for the compound:

• Store the sealed vial dry, cold (−20 °C for long-term storage) and protected from light.
• Let the vial reach room temperature before opening to prevent condensation.
• For cell-based assays, stock solutions are commonly prepared in DMSO; aliquot and freeze to avoid repeated freeze–thaw.
• Avoid prolonged exposure to strongly acidic aqueous conditions, which can hydrolyze the hydrazone linkage.
• Record the lot number in the lab notebook for every experiment so results can be traced to the COA.

For laboratories in the United States, a domestic supplier shortens transit time, keeps the material within one temperature and customs environment, and makes it easier to follow up on lot questions. When comparing suppliers, look for:

• lot-specific HPLC and MS documentation published or provided before purchase;
• correct identity data (CAS 303760-60-3, C₁₈H₁₄N₂O₂), with the compound described accurately as a small molecule;
• sealed, labelled vials with lot numbers;
• clear research-use-only terms and responsive technical contact.

NuRev Peptides ships from its California facility and lists the compound as SLU-PP-332 10mg, with lot documentation on the COA page. NuRev supplies SLU-PP-332 for laboratory research use only; it is not for human or veterinary use.