SLU-PP-332
SLU-PP-332 10mg
In stock
Ships from our California, USA facility
Lyophilized powder. Ships as a dry powder in a sealed vial and must be reconstituted before laboratory use.
Not for human consumption. This product is not a drug, food, or cosmetic, and is sold only to qualified researchers and licensed laboratories. By purchasing, the buyer agrees to use it in compliance with all applicable laws.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
- Batch Tested
- U.S. Fulfillment
- Research Only
Product Overview
SLU-PP-332 10mg
SLU-PP-332 is a synthetic small molecule, not a peptide, that acts as an agonist of the estrogen-related receptors ERRα, ERRβ and ERRγ. It is used in cell and animal research on energy metabolism, mitochondrial biogenesis and fatty acid oxidation. There are no published human trials and it is not an approved drug.
Receptor pharmacology
The estrogen-related receptors (ERRs) are orphan nuclear receptors that regulate genes involved in mitochondrial biogenesis, oxidative phosphorylation and fatty acid oxidation. Despite the name, they do not bind estrogen. SLU-PP-332 activates all three ERR subtypes, with its highest potency at ERRα, which makes it a tool compound for studying ERR-dependent transcription.
Published research
SLU-PP-332 was first described by Billon and colleagues (ACS Chemical Biology, 2023), who reported an ERRα-dependent gene-expression response in skeletal muscle and measured running endurance and oxidative muscle fiber content in mice. A second paper from the same group (Journal of Pharmacology and Experimental Therapeutics, 2024) examined energy expenditure and fatty acid oxidation in mouse models of diet-induced metabolic dysfunction.
Other groups have used the compound and related pan-ERR agonists to study cardiac fatty acid metabolism and mitochondrial function in mouse models (Xu and colleagues, Circulation, 2024) and mitochondrial function in the aging mouse kidney (Wang and colleagues, American Journal of Pathology, 2023). Analytical chemistry papers published in 2026 characterize its in vitro metabolites for laboratory detection methods.
Limitations of the evidence
All published findings come from cell culture and animal models. Results in mice describe those models under those conditions and do not establish effects in people.
Specifications
Contents: 10mg per vial
Form: Powder
Storage: Keep sealed, dry and protected from light; store cold
Quality and documentation
Batch-specific Certificates of Analysis from independent laboratories, showing purity and identity results, are listed under Batch Documentation on this page and in the COA library.
Research use only
All products on this site are for Research, Development use only. Products are Not for Human use of any kind. The statements made within this website have not been evaluated by the US Food and Drug Administration. The statements and the products of this company are not intended to diagnose, treat, cure or prevent any disease.
- Product Name
- SLU-PP-332 10mg
- CAS Number
- 303760-60-3
- Molecular Formula
- C18H14N2O2
- Molecular Weight
- 290.32 g/mol
- Form
- Lyophilized powder
- Storage
- Store sealed at −20 °C, dry and protected from light; 2–8 °C for short periods. Ships at ambient temperature
- Available sizes
- 10mg
- CAS Number
- 303760-60-3
- Molecular Formula
- C18H14N2O2
- Molecular Weight
- 290.32 g/mol
- Form
- Lyophilized powder
- Storage
- Store sealed at −20 °C, dry and protected from light; 2–8 °C for short periods. Ships at ambient temperature
Product Information
Product Overview
SLU-PP-332 10mg
SLU-PP-332 is a synthetic small molecule, not a peptide, that acts as an agonist of the estrogen-related receptors ERRα, ERRβ and ERRγ. It is used in cell and animal research on energy metabolism, mitochondrial biogenesis and fatty acid oxidation. There are no published human trials and it is not an approved drug.
Receptor pharmacology
The estrogen-related receptors (ERRs) are orphan nuclear receptors that regulate genes involved in mitochondrial biogenesis, oxidative phosphorylation and fatty acid oxidation. Despite the name, they do not bind estrogen. SLU-PP-332 activates all three ERR subtypes, with its highest potency at ERRα, which makes it a tool compound for studying ERR-dependent transcription.
Published research
SLU-PP-332 was first described by Billon and colleagues (ACS Chemical Biology, 2023), who reported an ERRα-dependent gene-expression response in skeletal muscle and measured running endurance and oxidative muscle fiber content in mice. A second paper from the same group (Journal of Pharmacology and Experimental Therapeutics, 2024) examined energy expenditure and fatty acid oxidation in mouse models of diet-induced metabolic dysfunction.
Other groups have used the compound and related pan-ERR agonists to study cardiac fatty acid metabolism and mitochondrial function in mouse models (Xu and colleagues, Circulation, 2024) and mitochondrial function in the aging mouse kidney (Wang and colleagues, American Journal of Pathology, 2023). Analytical chemistry papers published in 2026 characterize its in vitro metabolites for laboratory detection methods.
Limitations of the evidence
All published findings come from cell culture and animal models. Results in mice describe those models under those conditions and do not establish effects in people.
Specifications
Contents: 10mg per vial
Form: Powder
Storage: Keep sealed, dry and protected from light; store cold
Quality and documentation
Batch-specific Certificates of Analysis from independent laboratories, showing purity and identity results, are listed under Batch Documentation on this page and in the COA library.
Research use only
All products on this site are for Research, Development use only. Products are Not for Human use of any kind. The statements made within this website have not been evaluated by the US Food and Drug Administration. The statements and the products of this company are not intended to diagnose, treat, cure or prevent any disease.
- Product Name
- SLU-PP-332 10mg
- CAS Number
- 303760-60-3
- Molecular Formula
- C18H14N2O2
- Molecular Weight
- 290.32 g/mol
- Form
- Lyophilized powder
- Storage
- Store sealed at −20 °C, dry and protected from light; 2–8 °C for short periods. Ships at ambient temperature
Specifications
- Available sizes
- 10mg
- CAS Number
- 303760-60-3
- Molecular Formula
- C18H14N2O2
- Molecular Weight
- 290.32 g/mol
- Form
- Lyophilized powder
- Storage
- Store sealed at −20 °C, dry and protected from light; 2–8 °C for short periods. Ships at ambient temperature